Silicon carbide: a promising material for biosensor applications in blood

Green silicon carbide is a polycrystalline material with about 170 different crystal structures but the same stoichiometric ratio (i.e., all forms contain double layers of Si and C). In general, the two types of sic-6h biosensors have been shown to be non-toxic in general, i.e., the hexahedral SiC electrodes have been shown to be non-toxic in the past. Amorphous and crystalline silicon carbide, SiC and polycarbonate, have been used as coatings for many implantable biomedical devices, and their biocompatibility has been demonstrated for bone clinical research, prosthetic and cardiac stents.

The biocompatibility of three skin / connective tissue cell lines in vitro was established by planing and culturing on the surfaces of the main SiC polytypes, 3C SiC, 4H SiC and 6h SiC. The biocompatibility of three skin / connective tissue cell lines was evaluated by adhering to the substrate surface, successfully binding cells, and then proliferation.

 

In vitro, the same SiC polymorphs of nerve cell lines, as well as diamond (both nano and polycrystalline), glass, biocompatible polyimide and so on were reported. The most interesting thing about this work is that 3C SiC has the same biocompatibility as polyimide, while cell proliferation and adhesion on diamond surface are lower than that of SiC, especially 3C SiC. Therefore, the immutable biocompatibility of skin and connective tissue is completely different from that of nerve cells. We will see that the vascular system also shows differences in blood compatibility, and 3C SiC again shows the best performance.

 

The biocompatibility and other properties (such as mechanical and chemical resilience) of 3C SiC and the potential for making sensing devices or patterned grafts using traditional micromachining technologies make it an ideal candidate for vascular applications. However, this application will not be achieved until it is determined whether the material will stimulate thrombotic behavior that can cause thrombosis. In addition to being used as a biomaterial for biosensor applications in blood, silicon carbide can also be produced as abrasives. In addition, there are red shiliu abrasive.

Curious Asked on August 1, 2020 in Accessories.
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